Allergen Denaturation Study Services at Airmid Healthgroup
Airmid Healthgroup provides independent, scientifically rigorous allergen denaturation studies for manufacturers of cleaning products, surface treatments, and household consumer goods — generating the evidence needed to support allergen-neutralising claims and certification applications.
What Is Allergen Denaturation?
Allergen denaturation is the process by which a product chemically alters or destroys the structure of an allergen protein — rendering it unable to trigger an allergic immune response. Unlike allergen removal, which physically lifts allergens from a surface, denaturation neutralises them in place, making them biologically inactive.
For manufacturers of cleaning sprays, laundry products, surface treatments, and anti-allergen coatings, demonstrating allergen denaturation activity is a powerful and increasingly sought-after product claim — particularly in markets serving asthma and allergy sufferers.
Allergens Covered in Denaturation Studies
Airmid Healthgroup’s allergen denaturation studies can be conducted against a range of clinically relevant indoor allergens, including:
House Dust Mite
Der p 1 and Der f 1 — the most common triggers of perennial allergic rhinitis and asthma, found in bedding, carpets, and soft furnishings.
Pet Dander
Fel d 1 (cat) and Can f 1 (dog) — highly potent allergens that persist in indoor environments long after exposure.
Mould Allergens
Allergens from common indoor moulds such as Alternaria and Cladosporium — significant triggers for asthma, particularly in damp environments.
Cockroach Allergens
Bla g 2 and related proteins — important allergens in urban environments and a significant driver of childhood asthma.
How an Allergen Denaturation Study Works
- Surface Preparation: A defined surface — such as carpet, hard floor, upholstery, or textile — is inoculated with a known concentration of the target allergen under controlled conditions.
- Product Application: The test product is applied according to the manufacturer’s recommended instructions, including concentration, contact time, and application method.
- Sample Collection: After the specified contact time, allergen samples are collected from the treated surface using standardised extraction methods.
- Immunoassay Analysis: Collected samples are analysed using highly sensitive ELISA (enzyme-linked immunosorbent assay) techniques to determine the remaining immunologically active allergen — distinguishing between allergen that has been removed and allergen that has been denatured.
- Control Comparison: Results are compared against untreated controls and, where appropriate, water-only cleaning controls, to calculate the percentage denaturation achieved by the product.
- Reporting: A full scientific report is provided detailing methodology, results, and conclusions — ready to support product claims and certification applications.
Products That Can Be Tested
- Household cleaning sprays and surface cleaners
- Laundry detergents and fabric conditioners
- Anti-allergen surface treatments and coatings
- Carpet and upholstery cleaning products
- Air fresheners and indoor environment sprays
- Mattress and bedding treatment products
- Pet care and pet dander control products
Why Choose Airmid Healthgroup for Allergen Denaturation Studies?
ISO/IEC 17025 Accredited
Our laboratory holds ISO/IEC 17025 accreditation for specific allergen testing methods including cat (Fel d 1) and house dust mite (Der p 1) — ensuring results meet the highest standards of scientific rigour.
AAFA & Certification Partner
Airmid is a trusted partner of the Asthma and Allergy Foundation of America (AAFA) and the Asthma & Allergy Friendly® Certification Program — meaning our data is recognised by leading allergy certification bodies.
Decades of Allergen Expertise
With decades of experience in allergen science, aerobiology, and indoor environment research, our team understands the clinical significance of allergen denaturation and designs studies that produce commercially and scientifically meaningful results.
Claims-Ready Reporting
Our reports are structured to directly support product claims, regulatory submissions, and certification applications — giving your marketing and regulatory teams exactly what they need.
Request an Allergen Denaturation Study
Contact Airmid Healthgroup today to discuss your product and testing requirements. Our team will design a study that generates the evidence you need to support your allergen claims.
Frequently Asked Questions
What is the difference between allergen denaturation and allergen removal?
Allergen removal physically lifts allergens from a surface — for example, through vacuuming or wiping. Allergen denaturation chemically alters the allergen protein so that it can no longer trigger an immune response, even if it remains on the surface. Both are valid claims, but denaturation is a more specific and scientifically distinct mechanism that requires dedicated testing to demonstrate.
How is allergen denaturation measured in the laboratory?
Airmid uses ELISA (enzyme-linked immunosorbent assay) techniques to measure the immunological activity of allergens before and after product application. This allows us to quantify how much of the allergen remains biologically active — and therefore how effective the product is at denaturation.
Can allergen denaturation data support an Asthma & Allergy Friendly® certification?
Yes. As a certified partner of the Asthma & Allergy Friendly® programme, Airmid Healthgroup can conduct studies specifically designed to meet the programme’s requirements. Our data is recognised by the certification body and can be used directly in certification applications.
Can the study be conducted on different surface types?
Yes. Studies can be tailored to the surfaces most relevant to your product’s intended use — including hard floors, carpets, upholstery, textiles, mattresses, and other household surfaces. Contact us to discuss the most appropriate surface types for your product.
How long does an allergen denaturation study take?
Turnaround time depends on the number of allergens tested, surface types, and test conditions required. Most standard allergen denaturation studies are completed within 4–6 weeks of sample receipt. Contact our team for a project-specific timeline and quote.
